Evaluation the effects of Bupivacaine plus Magnesium Sulfate with Ropivacaine plus Magnesium Sulfate infiltration on postoperative pain

Comparison the effect of Bupivacaine plus Magnesium Sulfate with Ropivacaine plus Magnesium Sulfate infiltration on postoperative pain in patients undergoing lumbar laminectomy with general anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160430027677N18

Enrollment

Registered

2020-01-07

Start date

2019-01-21

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Generalized pain NOS

Interventions

Intervention 1: Intervention group: 70 mg ropivacaine 14 ml plus 1 ml magnesium sulfate 500 mg volume up to 20 ml with normal saline. Intervention 2: Intervention group: 70 mg of 14 ml bupivacaine plu

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: aged 18 to 65 years American Society of Anesthesiologists physical status classification I and II lumbar laminectomy with general anesthesia

Exclusion criteria

Exclusion criteria: Body mass index more than 35 kg/m2 Allergy to the drugs studied Seizure disease Severe systemic disease Coagulation Disorders mental Disorders A history of drug addiction

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Mean Arterial Blood Pressure. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: None Invasive Blood Pressure.;Mean pulse Rate. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Electrocardiogram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Oroumia University of Medical Sciences

sanesh@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026