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Effect of preoperative oral clonidine on shoulder pain in laparoscopic cholecystectomy with general anesthesia

Comparison the effect of preoperative oral clonidine and placebo on shoulder pain in laparoscopic cholecystectomy with general anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160430027677N17
Enrollment
64
Registered
2019-12-14
Start date
2017-04-20
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Generalized pain NOS

Interventions

Intervention 1: Intervention group: patients will receive clonidine 150 Microgram oral tablet, 90 minutes before surgery. Intervention 2: Control group: will be received oral placebo 90 minutes before

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Being at the age of 25 to 55 years old American Society of Anesthesiologists class I and II Elective laparoscopic cholecystectomy surgery

Exclusion criteria

Exclusion criteria: Hypertension Heart disease Gastritis kidney disease Lung disease Mental disease Addicted to all kinds of drugs People treated with beta-blockers People treated with methyl dopa Individuals treated with monoamine oxidase inhibitors use of analgesic drugs Body mass index above 25 kg / m 2

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
Mean Arterial Blood Pressure. Timepoint: Before anesthesia, In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: None Invasive Blood Pressure.;Mean pulse Rate. Timepoint: Before anesthesia, In recovery, during Laryngoscopy, 6, 12 and 24 hours after surgery. Method of measurement: Electrocardiogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Oroumia University of Medical Sciences

sanesh@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026