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Evaluation the effect of dexmedetomidine and remifentanil on posoperative pain

Comparison the effect of dexmedetomidine with remifentanil on postoperative pain after lumbar laminecthomy with general anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160430027677N13
Enrollment
60
Registered
2019-02-24
Start date
2018-01-20
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pain. Generalized pain NOS

Interventions

Intervention 1: Intervention group:Before anesthesia induction, 0.3 µg/50kg/min dexmedetomidine will be injected using a syringe pump for 10 minutes. During surgery 0.01-0.02 µg/kg/min dexmedetomidine

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: age group of 20-60 years old American Society of Anesthesiologists class I and II elective lumbar laminectomy

Exclusion criteria

Exclusion criteria: Patients with hypertension History of heart disease Bradycardia (Heart rate less than 50 per minute) arrhythmia People who have allergies to drugs used Gastritis Renal and pulmonary disease mental health problems Drug addict Patients treated with beta-blockers, methyl dopa, monoamine oxidase inhibitors Pain medications Body mass index greater than 25 kg/ m2

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: In recovery, 6, 12 and 24 hours after surgery. Method of measurement: Visual Analogue Scale.

Secondary

MeasureTime frame
The average need for an analgesic drug to control pain. Timepoint: In 12 hours after surgery. Method of measurement: milligram.;Mean Arterial Blood Pressure. Timepoint: time of laryngoscopy and during surgery. Method of measurement: None Invasive Blood Pressure.;Mean pulse Rate. Timepoint: time of laryngoscopy and during surgery. Method of measurement: Electrocardiogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahryar Sane

Oroumia University of Medical Sciences

sanesh@umsu.ac.ir+98 44 3223 4897

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026