diabetes. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Green cardamom supplements are prepared as 0.5 gram capsules. 2 capsule per meal (3 gram daily) should be consumed for 10 weeks. Intervention 2: placebo (flour breadcrumbs) supplements
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 59 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria Men and women between the age of 30–60 years old who have confirmed diagnosis of type 2 diabetes for more than 2 years; last HbA1C value greater than 7 %; Body Mass Index (BMI) between 25 and 35 kg/m2; Lipid-lowering drugs more than 3 months
Exclusion criteria
Exclusion criteria: Exclusion criteria Patients with any of the following criteria will be excluded: being on insulin regimen; use of fibrat(PPAR alpha ligand); TZD (PPAR gamma ligand); Smoking or alcohol consumption at least once a week in the past month; consumption of (at least once a week) herbal supplements; antioxidant; Multivitamin-Mineral in the past 3 months; pregnant and lactating women; have any gastrointestinal disorder, hepatic or renal disease, inflammatory disease, thyroid problems; any Chang in diet during the past 3 months, Consumers of anticoagulants (warfarin , heparin), antiplatelet drugs (Plavix), suppressor CNS (benzodiazepines), barbiturates (phenobarbital), antidepressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FBS. Timepoint: Before intervention, after intervention. Method of measurement: KIT.;FPI. Timepoint: Before intervention, after intervention. Method of measurement: KIT.;Hg A1c. Timepoint: Before intervention, after intervention. Method of measurement: kit.;Lipid profile. Timepoint: Before intervention, after intervention. Method of measurement: kit.;TAC. Timepoint: Before intervention, after intervention. Method of measurement: kit.;SOD. Timepoint: Before intervention, after intervention. Method of measurement: kit.;GPx. Timepoint: Before intervention, after intervention. Method of measurement: kit.;MDA. Timepoint: Before intervention, after intervention. Method of measurement: kit.;Sirt1. Timepoint: Before intervention, after intervention. Method of measurement: kit.;Irisin. Timepoint: Before intervention, after intervention. Method of measurement: kit.;VCAM. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;CD-163. Timepoint: Before intervention, after intervention. Method of measurement: kit.;ADMA. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;SBP. Timepoint: Before intervention, middle of intervention, after intervention. Method of measurement: mmhg by mercury manometer.;OX-LDL. Timepoint: Before intervention, after intervention. Method of measurement: KIT.;PON. Timepoint: Before intervention, after intervention. Method of measurement: KIT.;Apo A1 - apo B. Timepoint: Before intervention, after intervention. Method of measurement: KIT.;ICAM. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;NO. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;TNF-alfa. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;IL-6. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;HsCRP. Timepoint: Befor intervention, after intervention. Method of measurement: Kit.;DBP. Timepoint: Befor intervention, middle of | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGity Sotoudeh
Nutrition and Dietetics Faculty of Tehran Medical Sciences
Outcome results
None listed