Fracture of lower end of radius. Fracture of lower end of radius
Conditions
Interventions
Intervention 1: Control group: Classical Bier block will be performed by 3 mg/kg lidocaine. Intervention 2: Intervention group: patients will undergo Bier block with forearm tourniquet and 1.5 mg/kg l
Treatment - Drugs
Control group: Classical Bier block will be performed by 3 mg/kg lidocaine.
Intervention group: patients will undergo Bier block with forearm tourniquet and 1.5 mg/kg lidocaine combined with hematoma block (using 10 ml of 0.5% bupivacaine).
Sponsors
Vice Chancellor for Research, Shiaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18-70 years old age patients with distal fracture of radial bone who are candidate for reduction and closed pinning; years of age; ASA 1 and 2 Exclusion criteria: Peripheral neuropathy; sickle cell anemia; Reynaud disease; G6PD deficiency ; history of uncontrolled seizure; local infection or open wound in traumatized limb; severe coagulation defect; pregnancy; long term analgesic consumption or opioid dependency; patient refusal; abnormality in hepatic or renal elimination systems; inability to learn numerical rating scale (NRS) or PCA pump usage; peripheral vascular disease; severely overweight or underweight (BMI less than 18.5 and more than 30) ; hypersensitivity to local anesthetic drugs.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity during traction and reduction. Timepoint: once during reduction. Method of measurement: Numerical Rating Scale (NRS).;Pain intensity during the first 24 hour after operation. Timepoint: every 15 minutes for 1 hour, every hour till the end of 6th hour, every 2 hour till the end of 12th hour and then every 4 hour until the end of 24 hour after operation. Method of measurement: Numerical Rating Scale (NRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to the first request for analgesic. Timepoint: once at the moment of first request. Method of measurement: time elapsed from tourniquet deflation in minutes.;Time to the begining of tourniquet pain. Timepoint: once when the patient complained. Method of measurement: time elapsed from tourniquet inflation in minutes.;Total fentanyl administered during operation for tourniquet pain relieve. Timepoint: calculation of total fentanyl once at the end of operation. Method of measurement: total dosa in micrograms.;Frequency of occurence of symtoms of local anesthetic toxicity (convulsion, arrhythmia, tinnitus, perioral paresthesia, lightheadedness and vertigo). Timepoint: every 15 minutes during the first postoperative hour. Method of measurement: frequency (percent).;Administered morphine during the first 24 hour after operation. Timepoint: every 1 hour for 6 hours, every 2 hour till 12th hour and then every 4 hour till the end of the 24th hour after the operation. Method of measurement: injected dose in milligrams.;Frequency of occurence of morphine side effects (respiratory depression, pruritus, nausea and vomiting, urinary retention). Timepoint: every 4 hour after operation for 24 hours. Method of measurement: frequency (percent).;Patients` global satisfaction. Timepoint: once at the end of the study. Method of measurement: a 5 points scale: completely dissatisfied, dissatisfied, neutral, satisfied, completely satisfied. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRamin Tagvidi
Shiraz University of Medical Sciences
Outcome results
None listed