Skip to content

Cell therapy based on exosomes obtained from umbilical cord in Asherman syndrome

Cell therapy using co-treatment mesenchymal stem cells with exosomes obtained from the umbilical cord in infertile women due to Asherman syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160422027520N26
Enrollment
12
Registered
2025-01-11
Start date
2024-06-21
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asherman syndrome (intrauterine adhesions). Intrauterine synechiae

Interventions

Intervention 1: Intervention Group 1 received a single-dose injection containing 1 x 10^7 mesenchymal stem cells. A subendometrial injection of a cell suspension, prepared in 1 ml of normal saline, wa

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Secondary infertility or embryo transfer failure due to repeated IUA Desire to become pregnant Age less than 45 years old consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients under 20 years old and over 45 years old Patients who themselves or their spouses have abnormal karyotype or genetic and chromosomal disorders Patients with coagulation problems Patients who have an underlying chronic disease and have to take special drugs Patients whose HIV, HCV, or HBV test results are positive Patients who have a history of asthma and allergies to certain drugs Patients with intrauterine anomalies

Design outcomes

Primary

MeasureTime frame
Intrauterine adhesion rate. Timepoint: Before the intervention and after the intervention. Method of measurement: Using the ultrasound technique, we will evaluate the level of adhesion according to the standards of the American Fertility Association (AFS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Yousefi

Tabriz University of Medical Sciences

mehdi_yusefi@yahoo.com+98 41 3336 4665

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026