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Investigating the impact of autologous serum on the healing of face and jaw injuries

Autologous Conditioned Serum's impact on maxillofacial lesion healing

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160422027520N25
Enrollment
10
Registered
2024-12-10
Start date
2024-11-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Facial and jaw lesions. Fracture of mandible

Interventions

Intervention 1: The group that received processed autologous serum was the intervention group. In order to create processed autologous serum, 20 cc of blood is extracted from the patients cubital vein
each injection is one milliliter in volume. Using techniques from histology, histomorphometry, and CT-µ microcomputer tomography, the healing of the generated bone lesions will be examined one, three,

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Jaw dislocation or fracture accompanied with chin and tooth discomfort and edema Having trouble chewing food Tooth misalignment Teeth falling out or coming loose Joint pain in the jaw and trouble expanding the mouth

Exclusion criteria

Exclusion criteria: Individuals with underlying medical conditions Individuals having issues with coagulation Patients who are above 40 and younger than 18 Individuals with a history of asthma and medication allergies

Design outcomes

Primary

MeasureTime frame
The efficiency of processed autologous serum in treating lesions on the face and jaw. Timepoint: Examining the progress of the formed bone lesions one, three, and six months after the serum injection. Method of measurement: using techniques from microcomputer tomography, histomorphometry, and histology. Additionally, spectroscopy, bone density measurement, and gene expression study of bone morphogenetic proteins (BMP-2).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Yousefi

Tabriz University of Medical Sciences

mehdi_yusefi@yahoo.com+98 41 3336 4665

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026