Osteoarthritis. Erosive (osteo)arthritis
Conditions
Interventions
Intervention 1: Intervention group: In this group of patients, 10 ml of blood will be taken by PRP-specific syringe manufactured by Pishtaz Teb Zaman CO. and according to kit protocol, we will separat
Sponsors
Pishtaz Teb Zaman CO.
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Men and women between the ages of 18 and 75 with OA diagnosis based on the American College of Rheumatology Analog scale of knee pain (VAS) equal to or greater than 2.5 People with at least 4 months of history of pain or swelling in one or both knees Radiological classification scale Kellgren-Lawrence 1 or 2 The availability of individual during the study period BMI Between 20 and 35
Exclusion criteria
Exclusion criteria: People under the age of 18 and over 75 years Pregnant women or women who are breastfeeding People with malignancy,People with severe heart disease, uncontrolled diabetes mellitus, rheumatoid arthritis, hemorrhagic diseases, history of anemia, arthritis, fibromyalgia and chronic fatigue syndrome People with acetaminophen or vicodin addiction or a history of drug misuse History of cortisone injections in the last 6 weeks The use of non-steroidal anti-inflammatory drugs 1 week ago Having hemoglobin less than 11 g / dl and platelet count less than 150000 / mµ The use of inhibitors of platelet aggregation and anti-coagulation such as heparin History of knee surgery in the last 3 months Extraordinary deformation (varus >5?, valgus >5?)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determining knee pain. Timepoint: Before injection and 1, 3 and 6 months after the first injection. Method of measurement: Questionnaire (VAS).;Determination of knee function. Timepoint: Before injection and 1, 3 and 6 months after the first injection. Method of measurement: Questionnaire (WOMAC), Questionnaire (KOOS).;Determine the range of knee motion. Timepoint: Before injection and 1, 3 and 6 months after the first injection. Method of measurement: Manual joiniometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehdi Yousefi
Tabriz University of Medical Sciences
Outcome results
None listed