Gastric Ulcer. Stress Induced Gastric Ulcer
Conditions
Interventions
Intervention 1: Intervention group: Enteral feeding as 50 ml at beginning and then increasing 50 ml every 3 hours up to 200 ml every 3 hours. Intervention 2: Control group: Enteral feeding (same as th
Prevention
Intervention group: Enteral feeding as 50 ml at beginning and then increasing 50 ml every 3 hours up to 200 ml every 3 hours.
Control group: Enteral feeding (same as the intervention group) plus ranitidine amp, 50 mg every 8 hours as slow intravenous injection for 7 days.
Sponsors
Vice Chancellor for Research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Critically ill adult patients with indication of gastric ulcer prophylaxis without contraindication for enteral nutrition will be recruited. Exclusion criteria: Patients with history of active gastric ulcer in month before inclusion; gastric bleeding in time of hospitalization; coagulopathy; enteral feeding intolerance; severe burn; head trauma; increased intracranial pressure
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress induced gastric ulcer. Timepoint: At baseline and daily for 7 days. Method of measurement: Evaluation of gastrointestinal symptoms including gastric intolerance, coffe ground secretions from tube feeding, melena and hematemesis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications of gastric acid suppressant agents. Timepoint: At baseline and daily for 7 days. Method of measurement: Evaluation of patients for pneumonia and diarrehea. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Khalili
Tehran University of Medical Sciences
Outcome results
None listed