Lasix effect in kidney transplant patients

Lasix effect in two ways at once and infusion therapy in patients with a kidney transplant in Imam Reza Hospital Tabriz

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016042023559N3

Enrollment

Registered

2016-08-26

Start date

2016-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney transplant.

Interventions

Intervention 1: Bolus injection (one minute immediately before declamping arteries) Lasix during kidney transplant surgery. Intervention 2: Infusion injection(over 30 minutes immediately before declam

Treatment - Drugs

Bolus injection (one minute immediately before declamping arteries) Lasix during kidney transplant surgery.

Infusion injection(over 30 minutes immediately before declamping arterial) Lasix during kidney transplant surgery.

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: Included criteria: diagnosis of ESRD, indicated for kidney transplants; admission in Tabriz Imam Reza Hospital; male and female gender; 15-65 years old. Excluded criteria: patients with severe psychiatric problems; metastatic cancer patients; patients over 65 years old; patients with hemodynamic changes following their transplantation (reducing blood pressure less than 50 / 80 for more than half an hour); the constant drug abuse; chronic liver disease; reversible urinary tract infections; anomalies of the urinary system; aeortoiliac disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The volume of urine output. Timepoint: After vascular anastomosis to an hour, then every three hours for 24 hours then the second and third day after kidney transplant. Method of measurement: milliliter.	—

Secondary

Measure	Time frame
Na. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: meq/ml.;K. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: meq/ml.;BUN. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: mg/dl.;Creatinine. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: mg/dl.	—

Measure

Time frame

Na. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: meq/ml.;K. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: meq/ml.;BUN. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: mg/dl.;Creatinine. Timepoint: Before surgery and then daily until 4 days after kidney transplant. Method of measurement: mg/dl.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactProfessor Afshar Zomorrodi

Tabriz University of Medical Sciences

dr_afshar@hotmail.com+98 41 3555 3407

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026