Effect of supplementation in treatment of women with gestational diabetes

Clinical trial of the effect of zinc supplementation compared with the placebo on expressed levels of insulin receptor, PPAR-alpha and GLUT4 genes in newborns of women with gestational diabetes

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201604195623N76

Enrollment

Registered

2016-05-01

Start date

2016-02-20

Completion date

Unknown

Last updated

2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational diabetes. Diabetes mellitus in pregnancy, unspecified

Interventions

Intervention 1: Intervention group: Zinc supplements, 30 mg, daily, for 6 weeks orally. Intervention 2: Control group: Placebo capsule, daily for 6 weeks orally.

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients with gestational diabetes aged 18 to 40 years

Exclusion criteria

Exclusion criteria: Insulin-dependent diabetes Smoking History of kidney stones

Design outcomes

Primary

Measure	Time frame
Expressed levels of insulin receptor 1 gene. Timepoint: Dlivery time. Method of measurement: PCR.;Expressed levels of insulin receptor 2 gene. Timepoint: Dlivery time. Method of measurement: PCR.	—

Secondary

Measure	Time frame
Gene expression of PPAR-alpha. Timepoint: Delivery time. Method of measurement: PCR.;Gene expression of GLUT4. Timepoint: Delivery time. Method of measurement: PCR.;Gene expression of TGFB. Timepoint: Delivery time. Method of measurement: PCR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZatollah Asemi

Kashan University of Medical Sciences

asemi_r@yahoo.com+98 31 5546 3378

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026