Renal disease. Contrast-induced nephropathy
Conditions
Interventions
Intervention 1: Intervention: administration of omega-3, 12hr before percutaneous coronary intervention plus standard contrast-induced nephropathy preventive therapy (hydration). Intervention 2: Contr
Prevention
Intervention: administration of omega-3, 12hr before percutaneous coronary intervention plus standard contrast-induced nephropathy preventive therapy (hydration)
Control: just standard contrast-induced nephropathy preventive therapy (hydration)
Sponsors
Shiraz University of Medical Sciences, international branch
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria included GFR more than 60 ml/min/1.73 m2; the ages of 18 to 80 years; patients undergoing elective PCI. Exclusion criteria: Pretreatment with N-acetyl cystein or intravenous vitamin C; sensitivity or tolerance to ASA or Clopidogrel or omega-3; sever adverse effects to drugs
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cystatin C. Timepoint: Baseline and 24 hours after PCI. Method of measurement: Kit.;Serum creatinine. Timepoint: Baseline and 24 hours after PCI. Method of measurement: Kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast-induced nephropathy occurrence. Timepoint: 24 hrs after PCI. Method of measurement: Based on cystatin C. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzaneh Foroughinia
Shiraz University of Medical Sciences
Outcome results
None listed