Polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Group 1:Nigella Sativa capsule, 4 capsules 500 mg, 2 in the morning and 2 nights during the month, except during the period. if the bleeding did not happen in a month,the drug would
Treatment - Drugs
Group 1:Nigella Sativa capsule, 4 capsules 500 mg, 2 in the morning and 2 nights during the month, except during the period. if the bleeding did not happen in a month,the drug would be cut off for
Group 2: control group who received placebo from starch capsules, 4 capsules 500 mg, 2 in the morning and 2 nights during the month, except during the period if the bleeding did not happen in a month
Sponsors
School of Traditional Medicine, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Diagnosis of Polycystic Ovary syndrome by gynecologist, according to the National Institute of Health’s criteria; women aged 18-38 years old with irregular periods; having informed consent; Non-consumer of any hormonal medication and Metformin for at least three months prior the study. Exclusion criteria: Using anti-hypertensive, anti-cholesterol, anti- diabetic, insulin-sensitizing,medication; using aspirin and other anti-clotting medications, oral contraceptive and the anti-prostaglandin medications, parallel consumption of other herbal medications for disease treatment; patient with uncontrolled high blood pressure history, brain stroke, heart attack, cancer, cardiovascular disorders, liver disease, renal and thyroid disorders, type 1 or 2 diabetes; pregnancy and lactation; smoking.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 0ccurance of Menstrual bleeding. Timepoint: Before the intervention,1, 2, 3 and 4 months after the intervention. Method of measurement: Ask the patient.;Duration of menstural bleeding. Timepoint: Before intervention and 1,2,3, 4 month after intervention. Method of measurement: Ask the patient and complete tracking form.;Menstrual blood volume. Timepoint: Before intervention and1,2, 3, 4 month after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart (PBAC). | — |
Secondary
| Measure | Time frame |
|---|---|
| Menstrual cycle length. Timepoint: Before intervention and1,2, 3, 4 month after intervention. Method of measurement: Ask the patient and complete tracking form.;Serum LH. Timepoint: Before intervention and 3 month after intervention. Method of measurement: Serum analysis by ELIZA.;Total Testosterone. Timepoint: Before intervention and 3 month after intervention. Method of measurement: Serum analysis by ELIZA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Atieh Naeimi
School of Traditional Medicine, Shahid Beheshti University of Medical Sciences
Outcome results
None listed