Refractory epilepsy. Epilepsy
Conditions
Interventions
Intervention 1: Routine treatment plus oral omega-3 one tablet 1000 mg twice a day for 4 months. Intervention 2: Routine treatment plus a placebo tablet twice a day for 4 months.
Treatment - Drugs
Placebo
Routine treatment plus oral omega-3 one tablet 1000 mg twice a day for 4 months
Routine treatment plus a placebo tablet twice a day for 4 months
Sponsors
Vice-chancellor for Research the Technology, Hamadan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (a) age of 18 to 55 years; (b) having refractory epilepsy. Exclusion criteria: (a) pregnancy or breastfeeding; (b) having underling diseases such as lever disease, kidney disease, active infection, pulmonary disease, hypertension, dementia, and mental retardation; (c) catamenial epilepsy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessing the frequency of seizures. Timepoint: before treatment and every month for 4 months. Method of measurement: by taking history. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessing serum level of interleukin-6. Timepoint: before treatment and 4 months later. Method of measurement: by laboratory test.;Assessing serum level of TNF-a. Timepoint: before treatment and 4 months later. Method of measurement: by laboratory test.;Assessing electroencephalogram changes. Timepoint: before treatment and 4 months later. Method of measurement: by taking electroencephalogram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Shaghayegh Omrani
Farshchian Hospital
Outcome results
None listed