Melasma. Chloasma
Conditions
Interventions
Intervention 1: Control:Use 4% hydroquinone cream every night for 8 weeks. Intervention 2: Case:The use of methimazole 5% cream every night for 8 weeks.
Treatment - Drugs
Control:Use 4% hydroquinone cream every night for 8 weeks
Case:The use of methimazole 5% cream every night for 8 weeks
Sponsors
Vice chancellor for research, Shahid Beheshti University Skin Research Centerof Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:All the people in the age range of 50-20 years and all topical treatments for at least one month prior to study entry and are cut by a dermatologist examination with Wood's light examination (Wood) disease of epidermal melasma approved exclusion criteria and do not have;All people have informed consent to participate in the scheme. Exclusion criteria:Pregnancy and lactation;There Type of melasma 3Use of any treatment for melasma in the last month;Use of oral contraceptives and hormone therapy and medication have any phototoxic;Past medical history of any thyroid disorders in patients
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficasy of methimazole 5%cream in severity of melasma with change in colore. Timepoint: Every 4 Weeks. Method of measurement: MASI Score.;Efficacy of hydroquinone 4%cream in severity of melasma with change in colore. Timepoint: Every 4 weeks. Method of measurement: MASI score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Every four weeks. Method of measurement: Ask the patient. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactElham Olamaei
Skin Research Centers
Outcome results
None listed