Male infertility. Diseases of male genital organs
Conditions
Interventions
Intervention 1: In first group clomiphene (clomide, Iran hormone, Tehran/Iran, 25 milligram daily) will be given for 3 months. Intervention 2: In second group Letrozol (Letrofam, Iran Hormone/ Tehran/
Treatment - Drugs
In first group clomiphene (clomide, Iran hormone, Tehran/Iran, 25 milligram daily) will be given for 3 months.
In second group Letrozol (Letrofam, Iran Hormone/ Tehran/Iran, 2.5 milligram daily) will be given for 3 months. Semen Analysis will be assessed one week after last medications.( in one lab by one pers
Sponsors
Vice Chancellor for Research and Technology, Semnan University of Medical Sciences
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Inclusion criteria:Infertile men with sperm concentration, less than15 million per ml progressive motility, less than 32% total (progressive + non-progressive) motility,less than 40% , or morphologically normal forms,less than 4.0% ? exclusion criteria:Infertile male with Varicocele, Abnormal FSH and LH and TSH and Testestrone and Prolactin, Abnormal liver or kidney function tests.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm concentration. Timepoint: one week after last medication. Method of measurement: Semen analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sperm motility. Timepoint: one week after last medication. Method of measurement: Semen analysis.;Sperm morphology. Timepoint: one week after last medication. Method of measurement: Semen analysis.;Semen volume. Timepoint: one week after last medication. Method of measurement: Semen analysis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Azam Azargoon
Semnan University of Medical Sciences
Outcome results
None listed