Study the effect of spray coldamaris in recovery of oral mucositis in stem cellstransplantation patients.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: This study is a clinical study on 50 patients suffering from acute myeloma, pneumonia, and leukemia, who were hospitalized in the educational treatment ward of Shahid Ghazi Tabatabaei Hospital in Tabriz over the course of one year. After bone marrow transplantation, the mucositis incidence and severity were evaluated and its correlation with clinical and paraclinical findings was examined.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study is the improvement in the severity and extent of oral mucositis in patients undergoing stem cell transplantation, measured using a standard mucositis severity assessment scale (e.g., WHO Oral Mucositis Scale) on specific days after transplantation. Improvement includes the reduction of clinical symptoms of mucositis such as inflammation, pain, and oral ulcers. Timepoint: days 1 to 21 after transplantation. Method of measurement: WHO Oral Mucositis Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| The relationship between the severity of mucositis and laboratory markers, including ESR, LDH, fibrinogen, albumin, ferritin, and neutrophil count before transplantation, will be examined. Timepoint: Evaluation with laboratory tests one to three days before transplantation. Method of measurement: Laboratory tests and Statistical methods. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tabriz University of Medical Sciences