Gestational Diabetes. high-risk pregnancy
Conditions
Interventions
Intervention 1: Control group: Insulin will be started , if FBS or 2hpp glucose levels are not control (FBS>95/dl and 2hpp>120mg/dl) respectively by diet control and exercise. 40 patient (group A) wil
Treatment - Drugs
Control group: Insulin will be started , if FBS or 2hpp glucose levels are not control (FBS>95/dl and 2hpp>120mg/dl) respectively by diet control and exercise. 40 patient (group A) will be received In
Intervention group: 40 patients (group B) will be Glibenclamide starting with lowest requiring dose 1.25 mg (1/4 tab 5 mg) and will be increased by 1.5-2.50 mg weekly till reaching 15 mg.
Sponsors
Vice Chancellor Of Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Maternal age 20-40 years old; singleton pregnancy; gestational age and diagnosis of gestational diabetes will be given during pregnancy; healthy mothers with no renal diseases liver diseases and overt diabetes. Exclusion criteria: If the blood glucose is not controlled by the does of 15 mg glibanclamid they will be shifted to Insulin and will be excluded the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FBS & 2hpp. Timepoint: 4 time per day: over night fast and 2 hour post parandial diet (braekfast, lunch and dinner). Method of measurement: will be measured once a week by obestricians and twice weekly by the patients at home using Glucometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLida Tahamtani
Shiraz University of Medical Sciences
Outcome results
None listed