Opium dependence syndrome. Mental and behavioral disorders due to use of opioids : dependence syndrome
Conditions
Interventions
Intervention 1: Controls were received intravenous morphine 0.05 mg/kg and 5 cc of intramuscular distilled water. Intervention 2: Cases were received intravenous morphine 0.05 mg/kg and intramuscular
Treatment - Drugs
Controls were received intravenous morphine 0.05 mg/kg and 5 cc of intramuscular distilled water.
Cases were received intravenous morphine 0.05 mg/kg and intramuscular mixture of haloperidol 2.5 mg plus midazolam2.5 mg diluted in 5 cc of distilled water.
Sponsors
Vice chancellor for research, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 139 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Adult (18 years and older) patients who were opium dependent and had been admitted to the emergency department because of pain. Exclusion criteria: Age below 18 years; refuse to participation in the trial; inability to express or evaluate the pain (loss of consciousness, non-verbal patients due to articulation problems or mental decline); systolic blood pressure under 100 mm Hg; long QT interval in electrocardiogram and pregnancy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: 1,3and 6 hours post intervention. Method of measurement: Observation and clinical examination. | — |
Primary
| Measure | Time frame |
|---|---|
| Pain intensity. Timepoint: Pre-intervention and at 1,3,6 hours post intervention. Method of measurement: Numerical Rating Scale.;Morphine doses. Timepoint: 1,3 and 6 hours post-intervention. Method of measurement: Total doses of morphine (mg). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Afzalimoghadam
Tehran university of medical Sciences
Outcome results
None listed