male infertility. male infertility
Conditions
Interventions
Intervention 1: Intervention Group: 500 mg carob fruit Oral Capsules three times a day for 90 days. Intervention 2: Control group: oral 500 mg vitamin E capsules containing 100 mg of vitamin E and 400
Treatment - Drugs
Intervention Group: 500 mg carob fruit Oral Capsules three times a day for 90 days
Control group: oral 500 mg vitamin E capsules containing 100 mg of vitamin E and 400 mg starch
Sponsors
Research Deputy of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 20-45 years; married infertile man for at least one year with idiopathic abnormal spermogram about number; motility and morphology according to the World Health Organization (sperm count Less than 20 million per milliliter,type A mobility less than 25 percent and type B mobility less than 50% and normal morphology less than 30% ); non-smoking and non-alcoholism and drug users; desire to participate in the study; the ability to read and write Exclusion criteria: Being azospermic; infection and anatomical abnormalities of the genital tract such as duct blockage; to develop a varicocele ; surgery or need to do pelvic region surgery; diseases as cancer, liver and gallbladder, diabetes, thyroid, kidney failure, uncontrolled hypertension, cerebral hemorrhage, retinal hemorrhage, unilateral testicular atrophy; history of chemotherapy drugs, corticosteroids, anticoagulation, testosterone, antiandrogen; taking any other chemical, or certain herbal infertility drugs during the project and in the last quarter; recent consumption of vitamin E
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sperm count. Timepoint: Before and three months after intervention. Method of measurement: Semen analysis.;Sperm motility. Timepoint: Before and three months after intervention. Method of measurement: Semen analysis.;Sperm morphology. Timepoint: Before and three months after intervention. Method of measurement: Semen analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sexual function. Timepoint: Before and three months after intervention. Method of measurement: Sexual Function Questionnaire.;Side events. Timepoint: three months after intervention. Method of measurement: check list complete.;Satisfaction with treatment received. Timepoint: three months after intervention. Method of measurement: check list complete. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSima Sanagoo
Tabriz University of Medical Sciences
Outcome results
None listed