The Effect of Dietary Management Based on Iranian Traditional Medicine on patients with Non- Alcoholic Fatty Liver Disease

Investigation of the Effect of Dietary Management Based on Iranian Traditional Medicine on Insulin Resistance in patients with Non- Alcoholic Fatty Liver Disease: A controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016040927296N1

Enrollment

Registered

2016-05-03

Start date

2016-04-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatty liver disease. Diseases of liver

Interventions

Intervention 1: The case group will receive the dietary recommendations based on Iranian traditional medicine designed for fatty liver. This includes elimination of food items that are harmful to live

Lifestyle

Treatment - Drugs

The case group will receive the dietary recommendations based on Iranian traditional medicine designed for fatty liver. This includes elimination of food items that are harmful to liver and addition o

The control group will receive modern nutrition dietary recommendations. Each patient will complete the food diary questionnaire everyday which will be evaluated every month.Those patients that have f

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion: patient between 18 and 60years old; non alcoholic fatty liver (based on positive sonography and rule out of alcohol use; viral hepatitis; hemochromatosis; Wilson disease and autoimmune disease); no cirrhosis; patient with insulin resistance. Exclusion criteria: the reluctance of patients to continue to cooperate; insulin injection; food allergies; liver obstructive diseases and patient hospitalization.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Insulin resistance. Timepoint: Before intervention and 3 months after intervention. Method of measurement: HOMA-IR formula.	—

Secondary

Measure	Time frame
Body Mass Index. Timepoint: Before intervention and months1,2 and after intervention. Method of measurement: Scale and Meter.;Waist circumference. Timepoint: Before intervention and months1,2 and after intervention. Method of measurement: meter.;Alanine Aminotransferase. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Aaspartat Aminotransferase. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Fasting blood sugar. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Quality of life. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: Questionnaire (SF-36).;HgbA1C. Timepoint: Before intervention and at the end of intervention. Method of measurement: TINIA.;Serum Insulin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: ECL.;Serum Albumin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Ferritin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: ELISA.	—

Measure

Time frame

Body Mass Index. Timepoint: Before intervention and months1,2 and after intervention. Method of measurement: Scale and Meter.;Waist circumference. Timepoint: Before intervention and months1,2 and after intervention. Method of measurement: meter.;Alanine Aminotransferase. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Aaspartat Aminotransferase. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Fasting blood sugar. Timepoint: Before intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Quality of life. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: Questionnaire (SF-36).;HgbA1C. Timepoint: Before intervention and at the end of intervention. Method of measurement: TINIA.;Serum Insulin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: ECL.;Serum Albumin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: Spectrophotometer.;Ferritin. Timepoint: At the beginning of intervention and at the end of intervention. Method of measurement: ELISA.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Gorji

School of Traditional Medicine, Shahid Beheshti University of Medical Sciences

z.gorji@sbmu.ac.ir z.gorji@gmail.com+98 21 8877 3521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026