Effects of a 3 months treatment with selenium on serum Anti TPO level in patients with Hashimoto's thyroiditis compared with placebo

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016040918858N3

Enrollment

Registered

2017-09-24

Start date

2015-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hashimoto's thyroiditis. Autoimmune thyroiditis

Interventions

Intervention 1: Intervention group: Treatment with 200µg selenium pills once daily for 3 months+ Levothyroxin. Intervention 2: control group: Treatment with placebo once daily for 3 months+levothyroxi

Treatment - Drugs

Intervention group: Treatment with 200µg selenium pills once daily for 3 months+ Levothyroxin

control group: Treatment with placebo once daily for 3 months+levothyroxin

Eligibility

Sex/Gender

All

Age

15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Positivite Anti TPO; Age between 15-50 years; Lack of kidney and liver disorder; lack of hyperthyroidism; not pregnancy; Exclusion criteria: company dissatisfaction with the study; irregular drug use (no more than 20% of anticipated medications); patient's desire for each Time to leave the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anti TPO. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-international units per ml.;TSH. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-international units per ml.;T3. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-Nanograms per deciliter.;T4. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-Micrograms per deciliter.;Age. Timepoint: Before intervention. Method of measurement: Years.;Sex. Timepoint: Before intervention. Method of measurement: sex.	—

Measure

Time frame

Anti TPO. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-international units per ml.;TSH. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-international units per ml.;T3. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-Nanograms per deciliter.;T4. Timepoint: Before intervention and three months after intervention. Method of measurement: Laboratory kit-Micrograms per deciliter.;Age. Timepoint: Before intervention. Method of measurement: Years.;Sex. Timepoint: Before intervention. Method of measurement: sex.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomaye Gholami

Diabet Research Center, Yazd Shahid Sadughi University Of Mdical Science

somayegholami90@gmail.com+98 35 3728 0215

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026