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The Effect of Hypericum perforatum on early menopausal symptoms

The Effect of Hypericum perforatum on early menopausal symptoms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016040820053N2
Enrollment
80
Registered
2016-09-19
Start date
2009-06-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menopausal symptoms. Menopausal and female climacteric states

Interventions

Intervention 1: For 2 months Perforan pills contain 330 µg hypericum tree times a day. Intervention 2: For 2 months Placebo pills 3 times a day.
Treatment - Drugs
For 2 months Perforan pills contain 330 µg hypericum tree times a day
For 2 months Placebo pills 3 times a day

Sponsors

Jundishapur Ahvaz University of Medical Sciences, Vice Chancellor Of Research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age45-60 years, amenorrhea for at least 12 months, at least two symptoms of menopause, according to Kupperman index, patients could read and write; abnormal menopause induced ex. hysterectomy, oophorectomy or radiation therapy for known systemic disease such as endocrine disorders (thyrotoxicosis), dietary intake of phyto estrogen and specific regimes , having physical and mental diseases, sexual hormones consumption , sensitivity to herbal drugs, athletes women, antidepressants consumption, herbal medicines consumption, body mass index higher than 30 were excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hot flushes. Timepoint: Before the study and weeks 2, 4, 6 and 8. Method of measurement: Kupperman’s index.;Depression. Timepoint: Before the study and weeks 2, 4, 6 and 8. Method of measurement: Kupperman’s index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlieh Etemadi Kermani

Ahvaz Jondishapour university of medical sciences

alieh_a@yahoo.com+98 61 4362 0065

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026