Comparission of the effect of Paracetamol with Lidocaine

Comparission of the effect of Paracetamol with Lidocaine in prevention of the pain of the injection of propofol

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201604074131N1

Enrollment

200

Registered

2016-05-30

Start date

2016-08-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention 1: Iv injection of 40 mg Lidocaine in 5 ml normal saline before infusion of Propofol. Intervention 2: IV injection of 2 mg/kg Paracetamol in 5 ml normal saline before Propofol. Intervent

Treatment - Drugs

Placebo

Iv injection of 40 mg Lidocaine in 5 ml normal saline before infusion of Propofol

IV injection of 2 mg/kg Paracetamol in 5 ml normal saline before Propofol

IV injection of 40 mg Lidocaine in 20 ml normal saline before Propofol

IV injection of 5 ml normal saline before Propofol

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : patients with aged between 20 -60 years old ;elective surgery ;general anesthesia with Propofol ; anesthetic classes 1 or 2 ;not using sedative agents before surgery ;voluntary agreement to participate Exclusion criteria : occuring serious side effects

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: throughout intervention. Method of measurement: Visual Anlalog Scale (VAS ).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ali Mohammadian

Ardabil University of Medical Sciences

a.sharghi@arums.ac.ir+98 45 3351 0052

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026