Effect of alprazolam and clonazepam on blood glucose in adult panic patients

Assessment for compare the effect of alprazolam and clonazepam on blood glucose in adult panic patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016040722991N3

Enrollment

Registered

2016-04-21

Start date

2016-04-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

panic disorder. Panic disorder [episodic paroxysmal anxiety]

Interventions

Intervention 1: Intervention group 1: 1.5-4 milligram per day alprazolam besides 50-200 milligram sertraline for 12 weeks. Intervention 2: Intervention group 2: 1.5-4 milligram per day clonazepam besi

Treatment - Drugs

Intervention group 1: 1.5-4 milligram per day alprazolam besides 50-200 milligram sertraline for 12 weeks

Intervention group 2: 1.5-4 milligram per day clonazepam besides 50-200 milligram sertraline for 12 weeks

Control group: 50-200 milligram sertraline per day for 12 weeks

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18 years and over; filling out the informed consent form; psychiatric diagnosis of panic disorder; no desire to be pregnant during the study and to use proper contraceptive; no use of psychoactive drugs at least in one week before entering the study Exclusion criteria: active suicidal thoughts; disorders in which it is contraindicated to use sertraline, alprazolam and clonazepam; past history or having psychotic or bipolar disorders; pregnancy or breast feeding; uncontrolled convulsion disorders; a personality disorder in severity which worsens the evaluation of efficacy and safety of treatment; co-treatment with other psychotropic drugs; diabetes mellitus

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Fasting blood glucose. Timepoint: 12th week. Method of measurement: blood test.;Two hours post-prandial blood glucose. Timepoint: 12th week. Method of measurement: blood test.;Hemoglubine A!C. Timepoint: 12th week. Method of measurement: blood test.	—

Secondary

Measure	Time frame
The number of panic attacks. Timepoint: weekly. Method of measurement: psychiatric visit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSussan Moudi, MD

Babol University of Medical Sciences

sussan.mouodi@gmail.com+98 11323268823

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026