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Efficacy of autologous plasma therapy on clinical symptoms of Chronic Spontaneous Urticaria

Clinical Trial on efficacy of autologous plasma therapy on clinical symptoms of Patients with Chronic Spontaneous Urticaria Compared with no treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016040627260N1
Enrollment
30
Registered
2016-05-10
Start date
2016-04-08
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Spontaneous Urticaria. Other urticaria (Urticaria: chronic, recurrent periodic)

Interventions

Patients will be divided into idiopathic and autoimmune forms of urticaria after the autologous plasma skin test. After consent to participate in the study, 5cc of brachial vein blood will be sampled
Treatment - Other

Sponsors

Vice-chancellor for Research of Bushehr University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are urticaria for more than 2 months; Age over than 15 year old; Consent to participate in the study; Negative Prick skin test for common inhalation and food allergens and normal findings in Lab data such as CBC (Complete Blood Count), ANA (Antinuclear antibody), ESR (Erythrocyte Sedimentation Rate), LFT (Liver Function Test), U/A (Urine Analysis) and S/E (Stool Exam). Exclusion criteria are Pregnancy; Physical urticaria; Use of corticosteroid and immunosuppressive agents during the last 6 weeks; Use of drugs other than antihistamine and other systemic diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Qualitative clinical symptoms of urticaria. Timepoint: Before the treatment, every week during the treatment and one week after the treatment. Method of measurement: Changes in DLQI (Dermatology Life Quality Index).

Secondary

MeasureTime frame
Quantitative clinical symptoms of urticaria. Timepoint: Before the treatment, every week during the treatment for 10 weeks and one week after the treatment. Method of measurement: Changes in TSS (Total Symptoms Score) index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfshin Shirkani

Faculty of Medicine. Bushehr University of Medical Sciences.

a.shirkani@bpums.ac.ir+98 77 3345 5388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026