the effect of topical tranexamic acid in compare with topical hydroquinone4% is used in women with melasma

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016040627220N2

Enrollment

Registered

2016-06-13

Start date

2015-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

melasma. chloasma

Interventions

Intervention 1: control group:apply topical hydroquinone4% seagull company nightly for 3 months. Intervention 2: intervention group:apply topical tranexamic acid 5% manufactured by pharmacy of Hazrat

Treatment - Drugs

control group:apply topical hydroquinone4% seagull company nightly for 3 months

intervention group:apply topical tranexamic acid 5% manufactured by pharmacy of Hazrat Rasool Akram hospital of Tehran nightly for 3 months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: inclusion criteria: 1.female gender,2.suffering melasma exclusion criteria: 1.lack of compliance to continue the treatment,2.developed side effect of the treatment.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Melasma. Timepoint: 8 weeks and 12 weeks later. Method of measurement: photography.	—

Secondary

Measure	Time frame
Rate of the lightening of the skin affected with melasma. Timepoint: 8 weeks and 12 weeks later. Method of measurement: photography and determining rate of MASI.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Najm-alsadat atefi

Iran University Medical Sciences

Dalvandb@tak.iums.ac.ir+98 21 6650 2040

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 26, 2026