Thalassaemia. Beta thalassaemia
Conditions
Interventions
Intervention 1: Intervention group : Patients with thalassemia major will receive two capsules daily for four months each capsule contains 150 mg extract oak. Intervention 2: Control group: thalassem
Treatment - Drugs
Placebo
Intervention group : Patients with thalassemia major will receive two capsules daily for four months each capsule contains 150 mg extract oak
Control group: thalassemia Patients in the control group will receive two placebo capsule daily for four months.
Sponsors
Sharekord University of Medical Sciences
Eligibility
Sex/Gender
All
Age
10 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Patients with thalassemia major 2. patients with regular blood transfusions 3. Patients who received chelation therapy (desferal) at least four days a week 4. 10-60 years old 5. getting informed consent Exclusion criteria: 1. Under 10 years 2. Positive Hepatitis 3. Positive HIV 4. heart failure and chronic kidney disease 5. peregnance 6. chelating not answer or other chelating use.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ferritin. Timepoint: Before and after of study. Method of measurement: ELIZA.;Iron. Timepoint: Before and after of study. Method of measurement: Biochemical Auto analizer.;Glutathione peroxidase. Timepoint: Before and after of study. Method of measurement: Spectrophotometric.;Catalase. Timepoint: Before and after of study. Method of measurement: Spectrophotometric.;Superoxide dismutase. Timepoint: Before and after of study. Method of measurement: Spectrophotometric.;Carbonyl protein. Timepoint: Before and after of study. Method of measurement: Spectrophotometric.;Malondialdehyde. Timepoint: Before and after of study. Method of measurement: HPLC.;Total Capacity Antioxidant. Timepoint: Before and after of study. Method of measurement: Spectrophotometric. | — |
Secondary
| Measure | Time frame |
|---|---|
| Alanin Transferase. Timepoint: Before and after of study. Method of measurement: Biochemical auto analyzer.;Aspartate amino transferase. Timepoint: Before and after of study. Method of measurement: Biochemical auto analyzer.;Triglyceride. Timepoint: Before and after of study. Method of measurement: Biochemical auto analyzer.;Cholestrol. Timepoint: Before and after of study. Method of measurement: Biochemical auto analyzer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Babamir
Sharekord University of Medical Science
Outcome results
None listed