Anxiety. Generalized anxiety disorder
Conditions
Interventions
Intervention 1: Intervention group, 5mg Chlordiazepoxide, once, The night before of surgery, second, in operation day, before anesthesia induction. Intervention 2: Control group, Placebo, once, The ni
Prevention
Placebo
Intervention group, 5mg Chlordiazepoxide, once, The night before of surgery, second, in operation day, before anesthesia induction
Control group, Placebo, once, The night before of surgery, second, in operation day, before anesthesia induction
Sponsors
Vice Chancellor Research of Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: full consciousness; age between 18 to 60 years; hospitalization period for at least a day before surgery; no diagnosed mental disorder and under treatment by anti anxiety drugs. Exclusion criteria: Under treatment by ß2 antagonist drug like Salbutamol or anti asthma drugs such as Theophylline; Chronic Diabetic; Hepatic and Renal Failure; patients that undergoing major surgery for two or more time.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anxiety. Timepoint: The night before surgery in Ward (before Drug or Placebo use) and the morning of surgery in Operation Room. Method of measurement: STAI Anxiety questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Potassium. Timepoint: The night before surgery in Ward (before Drug or Placebo use) and the morning of surgery in Operation Room. Method of measurement: Blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Abdolmajid Gholinataj Jelodar
Tehran University of Medical Science
Outcome results
None listed