habitual miscarriage. Habitual aborter
Conditions
Interventions
Intervention 1: No intervention for control group. Intervention 2: Amp.clexan 40 mg daily subcutanouse until to end of study for intervention group.
Treatment - Drugs
Amp.clexan 40 mg daily subcutanouse until to end of study for intervention group
Sponsors
Avicenna research institute
Eligibility
Sex/Gender
Female
Age
67 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: ;HX of 1st recurrent miscarriage ;age 18-40 ;normal anti phospholipid test ;normal thrombophilic test ;normal immunologic test ;no anatomical abnormality(normal HSG) ;normal karyotype ;normal ovarian reserve ;normal spermogram -Exclusion criteria: ;previous treatment with LMWH ;HX of thromboembolic disease ;any abnormality in HSG , karyotype , thrombophilic & anti phospholipid & immunologic test ;ectopic pregnancy during research ;not have 1st trimester abortion ;HX of hemorrhagic disease or allergy to heparin ;age 40 ;poor ovarian reserve ;treatment stopping by paitient ;long period to get pregnancy and need to ART
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abortion rate. Timepoint: end of 1st trimester of pregnancy. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ectppic pregnancy rate. Timepoint: 5th week of pregnancy. Method of measurement: sonography & BhCG titer.;Side effect rate of clexan. Timepoint: during of study. Method of measurement: Hemorrhagic complication.;Trombocytopenia. Timepoint: During of study. Method of measurement: Platelet count in blood sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Azam Mohammad Akbari
Avicenna Infertility Clinic
Outcome results
None listed