Comparison of dexmedetomidine-induced analgesia with ketamine

Comparison of dexmedetomidine and ketamine on analgesia among patients with lumbar fusion who use pain pump after surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160403027191N4

Enrollment

165

Registered

2020-12-16

Start date

2019-08-22

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar fusion. Fusion of spine, lumbar region

Interventions

Intervention 1: Intervention group 1: Intervention group: Group K: For group K patients, infusion of 50mg Ketamine, 20mg intravenous morphine, which reached 100 cc with normal saline, was given by PCA

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for lumbar fusion surgery Age range 18-65 years Patients with ASA class I and II

Exclusion criteria

Exclusion criteria: History of previous spinal surgery Allergy to ketamine or dexmedetomidine Liver or kidney problems

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Visual analogue scale (VAS).	—

Secondary

Measure	Time frame
Nausea and vomiting. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.;Taking medication. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.;Duration of hospitalization. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Patient file.;Time of return from Ileus. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.	—

Measure

Time frame

Nausea and vomiting. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.;Taking medication. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.;Duration of hospitalization. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Patient file.;Time of return from Ileus. Timepoint: At times 2, 4, 6, 12, 18, 24 hours after surgery. Method of measurement: Checklist.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolmajid Gholi Nataj Jelodar

Mazandaran University of Medical Sciences

gholinataj54@mazums.ac.ir+98 11 3325 5348

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026