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Effect of Meperedin and Ketamin in prevention of shivering

Comparison effects of intravenous ketamine with intrathecal meperidine in prevention of shivering in elective orthopedic surgery of lower extremity with spinal anesthesia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160403027191N3
Enrollment
150
Registered
2020-12-07
Start date
2017-03-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering.

Interventions

Intervention 1: Group K: Bupivacaine 0.5% 15 mg, which was increased to 4 ml with normal saline, was injected intrathecally, and immediately after spinal anesthesia, ketamine 0.5 mg / kg, which was re

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patient's desire to participate in the study and gain informed consent Elective lower extremity orthopedic surgery under spinal anesthesia Age>18and Age<65 ASA 1 and 2

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The amount of shivering. Timepoint: From three minutes after the onset of anesthesia to two hours later at twenty-minute intervals. Method of measurement: Shivering chart.

Secondary

MeasureTime frame
Body temperature. Timepoint: From three minutes after spinal anesthesia to two hours later at intervals of every twenty minutes. Method of measurement: Termometr.;Mean Arterial Pressure. Timepoint: From three minutes after spinal anesthesia to two hours later at intervals of every twenty minutes. Method of measurement: Saadat automatic pressure gauge.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolmajid Gholi Nataj Jelodar

Mazandaran University of Medical Sciences

gholinataj54@mazums.ac.ir+98 11 3325 5348

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026