Premenstrual dysphoric disorder. An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual
Conditions
Interventions
Intervention 1: All patients in first intervention group, taking Flaxseed oil soft gel over three menstrual cycles from 7 days before starting cycle for 14 days, fasting and before sleep. Interventio
Treatment - Drugs
Placebo
All patients in first intervention group, taking Flaxseed oil soft gel over three menstrual cycles from 7 days before starting cycle for 14 days, fasting and before sleep
All patients in second intervention group, taking placebo soft gel over three menstrual cycles from 7 days before starting cycle for 14 days, fasting and before sleep
Sponsors
Vice Chancellor for research of Tehran university School of Traditional Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 18 and 35; Regular menstrual cycles (21-35 days) in the past two months; No smoking, tobacco and drugs; Have premenstrual dysphoric disorder according to PSST questionnaire; No use of other drugs and effective supplementation on premenstrual syndrome for 2 months before intervention; Not taking oral contraceptives; No history of psychiatric drugs and psychotropic substances in the past 6 months; No history of physical or mental illness during 3 months before study; No depression based on the SCL-90-R; No stress in the last three months like dead relatives or marriage or surgery, No pregnancy; No lactating Exclusion criteria: consumption of other drugs and supplements effective in the treatment of premenstrual syndrome during study; oral contraceptive pills during intervention; Report any allergies or side effects during the study; Inappropriate use of drugs; get pregnant; Cancel study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Premenstrual dysphoric disorder severity. Timepoint: before and during the three months of intervention. Method of measurement: PSST questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Response to treatment. Timepoint: After intervention. Method of measurement: CGI-I questionnaire.;Patient satisfaction. Timepoint: After intervention. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFereshteh Ghorat
Tehran University of medical sciences
Outcome results
None listed