Comparison of etomidate anesthesia and thiopental anesthesia on duration of seizure and amnesia after electroconvulsive therapy

Comparison of etomidate and thiopental on seizure duration and amnesia in electroconvulsive therapy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016040212123N4

Enrollment

Registered

2017-03-28

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: psychiatric disorders. Condition 2: psychiatric disorders. Schizophrenia, schizotypal and delusional disorders Bipolar affective disorder

Interventions

Intervention 1: In intervention group induction of anesthesia achieves with etomidate (0.3 mg/kg) and succinylcholine (0.5 mg/kg), ventilation with 100% oxygen and monitoring of pulse rate, blood pre

Treatment - Drugs

In intervention group induction of anesthesia achieves with etomidate (0.3 mg/kg) and succinylcholine (0.5 mg/kg), ventilation with 100% oxygen and monitoring of pulse rate, blood pressure and SPo2 w

In control group induction of anesthesia achieves with thiopental (3mg/kg) and succinylcholine (0.5 mg/kg), ventilation with 100% oxygen and monitoring of pulse rate, blood pressure and SPo2 will be

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion: male or female patients at the age of 18 to 40 years old who are candidate for ECT Exclusion:patients with ASAclass3 or higher, use of antiepileptic drugs and anesthesia complications

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Duration of seizure. Timepoint: start of tonic contractions to end of clonic contractions. Method of measurement: second ( use of chronometer).;Retrograde memory. Timepoint: One day before ECT,before induction of anesthesia, at the end of recovery, 4 hours later, the next day and once a week for a month after ECT procedures. Method of measurement: Asking 10 questions that patient can answer, like tel. number, patient's high school name or president name. These questions will repeat for detection of retrograde amnesia.;Anterograde memory. Timepoint: One day before ECT, before induction of anesthesia, at the end of recovery, 4 hours later, the next day and once a week for a month after ECT procedures. Method of measurement: Showing 10 picture cards (car, house, airplane…) and then ask the patient to find them among 15 picture cards. If the patient recall all cards, he/she take 10 points.	—

Measure

Time frame

Duration of seizure. Timepoint: start of tonic contractions to end of clonic contractions. Method of measurement: second ( use of chronometer).;Retrograde memory. Timepoint: One day before ECT,before induction of anesthesia, at the end of recovery, 4 hours later, the next day and once a week for a month after ECT procedures. Method of measurement: Asking 10 questions that patient can answer, like tel. number, patient's high school name or president name. These questions will repeat for detection of retrograde amnesia.;Anterograde memory. Timepoint: One day before ECT, before induction of anesthesia, at the end of recovery, 4 hours later, the next day and once a week for a month after ECT procedures. Method of measurement: Showing 10 picture cards (car, house, airplane…) and then ask the patient to find them among 15 picture cards. If the patient recall all cards, he/she take 10 points.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Nourian MD

Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran

javadnourian@shmu.ac.ir+98 23323342001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026