The efficacy of Flaxseed oil on the vaginal dryness

Comparison of the effectiveness of Flaxseed oil vaginal gel with lubricant vaginal gel on the vaginal dryness in postmenopausal women

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160402027170N2

Enrollment

Registered

2017-12-20

Start date

2018-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal dryness in postmenopausal women. Postmenopausal atrophic vaginitis

Interventions

Intervention 1: Intervention group: Flaxseed oil vaginal gel with the applicator 3 nights a week for 8 consecutive weeks. Intervention 2: Control group: Lubricant vaginal gel with the applicator 3 nig

Treatment - Drugs

Intervention group: Flaxseed oil vaginal gel with the applicator 3 nights a week for 8 consecutive weeks

Control group: Lubricant vaginal gel with the applicator 3 nights a week for 8 consecutive weeks

Eligibility

Sex/Gender

Female

Age

45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Postmenopausal women aged 65-45 Menopause diagnosis with one of these symptoms: had a history of at least 1 year of amenorrhea or a high level of follicle-stimulating hormone (FSH) above 40 or bilateral oophorectomy

Exclusion criteria

Exclusion criteria: History of oral estrogen consumption in the 8 weeks prior to study Active vaginal infection Systemic disease

Design outcomes

Primary

Measure	Time frame
Score of vaginal dryness in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of vaginal burning in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of vaginal itching in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of dyspareunia in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).	—

Measure

Time frame

Score of vaginal dryness in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of vaginal burning in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of vaginal itching in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).;Score of dyspareunia in Visual Analoge Scale (VAS). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Visual Analoge Scale (VAS).

—

Secondary

Measure	Time frame
Score of Vaginal Health Index (VHI). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Vaginal Health Index (VHI) questionnaire.;Percentage of Vaginal Maturation Index (VMI). Timepoint: Before the intervention begins, the end of the intervention. Method of measurement: Vaginal Maturation Index (VMI) questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNejatbakhsh Fatemeh

Tehran University of Medical Sciences

Nejatbakhsh@tums.ac.ir+98 21 8899 0837

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026