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Effect of supplementation in treatment of women with polycystic ovary syndrome

Clinical trial of the effect of soy isoflavone supplementation compared with the placebo on lipid profiles in women with polycystic ovary syndrome

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201604015623N70
Enrollment
70
Registered
2016-04-07
Start date
2016-02-29
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Soy isoflavone capsule, 50 mg, daily for 12 weeks orally. Intervention 2: Control group: Placebo capsule, daily for 12 weeks orally.
Treatment - Drugs
Intervention group: Soy isoflavone capsule, 50 mg, daily for 12 weeks orally.

Sponsors

Vice chancellor for research, Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with PCOS according to Rotterdam criteria; higher than 5 years of their disease; aged 18 to 40 years. Exclusion criteria: Unwillingness to cooperate.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Total cholesterol. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Enzymatic kit.;Triglycerides. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Enzymatic kit.;HDL-cholesterol. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Enzymatic kit.

Secondary

MeasureTime frame
Hs-CRP. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Elisa kit.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026