distal radial fracture. Injury to the wrist and hand
Conditions
Interventions
Intervention 1: Intervention group: the first group, in this group midazolam (Darupakhsh Co, Iran) was given with dose of 0.1 mg /kg, and Fentanyl (Abu Rayhan CO, Iran),with dose of 3 µg/kg with wit
Treatment - Drugs
Intervention group: the first group, in this group midazolam (Darupakhsh Co, Iran) was given with dose of 0.1 mg /kg, and Fentanyl (Abu Rayhan CO, Iran),with dose of 3 µg/kg with with titarting dose
Intervention group: The second group, in this group, dexmedethomidine (Huspiria of USA, Behestan Daroba) was given with a dose of 1 mg/kg with 10-minute intravenous infusion and fetanyl(Abu Ravihan
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: All patients aged 18 to 60 years old who referred to the emergency department with a distal radial fracture
Exclusion criteria
Exclusion criteria: patient who taking antihypertensive or antihistaminic drugs patient aged less than 18 years Severe associated injury include: Head trauma and deceased level of consciousness (GCS <15), Severe chest trauma Cervical spine trauma with unstable fracture Patients with hemodynamic instability Patients with mental retardation Patients with a history of heart disease (bradycardia and any AV heart block) pregnant patient history of allergy to midazolam, fentanyl and dexmedethomidine addiction to opioids and substance abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Before inducing sedation and analge- After the procedure and complete awakining. Method of measurement: Visual analog scale(VAS).;Hypertension. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic barometric( Saadat Factory).;Heat rate. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic Monitor( Saadat Factory).;SPO2. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Electronic Pulsoximer( Saadat Factory).;Respiratory rate. Timepoint: Before, during and immediately after the completion of procedure. Method of measurement: Clinical examination(Obsevation). | — |
Secondary
| Measure | Time frame |
|---|---|
| Apnea. Timepoint: during and immediately after the completion of procedure. Method of measurement: close observation.;Bradycardia. Timepoint: during and immediately after the completion of procedure. Method of measurement: Electronic Monitor( Saadat Factory).;Nausea and vomiting. Timepoint: during and immediately after the completion of procedure. Method of measurement: close obsevation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Arhami Dolatabadi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed