Effect of folic acid on prevention of preeclamsia consequences

Evaluation of the effect of High dose Folic acid on endothelial dysfunction in preeclamptic patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016032727135N1

Enrollment

Registered

2016-04-24

Start date

2015-06-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-eclampsia. Pre-eclampsia, unspecified

Interventions

Intervention 1: folic acid, tablet, 50 mg, once daily, from the begining of the intervention until 2 months after delivery. Intervention 2: placebo, tablet, PO, from the begining of the intervention u

Treatment - Drugs

folic acid, tablet, 50 mg, once daily, from the begining of the intervention until 2 months after delivery

placebo, tablet, PO, from the begining of the intervention until 2 months after delivery

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnancy; preeclampsia Exclusion criteria: Major underlying diseases; incomplete drug consumption

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Flow mediated dilation of brachial artery. Timepoint: before and after intervention. Method of measurement: High resolution B-mode ultrasonographic.	—

Secondary

Measure	Time frame
Lipid profile. Timepoint: before and after intervention. Method of measurement: laboratory test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKian Heshmat

Isfahn University of Medical Sciences

saeide.bahrani@gmail.com+98 31 3333 3333

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026