Comparing the effect of Pethidine, Ketamin and Ondansetron to prevent postoperative shivering in elective removal of gallbladder under general anesthesia

Comparing the effect of Pethidine, Ketamin and Ondansetron to prevent postoperative shivering in elective cholecyctectomy under general anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016032326340N1

Enrollment

160

Registered

2016-03-23

Start date

2015-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prevention of postoperative shivering. Complication of surgical and medical care, unspecified

Interventions

Intervention 1: Group A

Received Pethidine 0.4 mg/ kg. Intervention 2: Group B

Received Ketamin 0.25 mg/kg. Intervention 3: Group C

Received Ondansetron 0.1 mg/kg. Intervention 4: Group D

Received Normal Saline 2 cc.

Treatment - Drugs

Group A

Received Pethidine 0.4 mg/ kg

Group B

Received Ketamin 0.25 mg/kg

Group C

Received Ondansetron 0.1 mg/kg

Group D

Received Normal Saline 2 cc

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclision criteria: Having Laparoscopic cholecyctectomy surgery; age between 20-50 Exclusion criteria: Smoking; addiction; cardiovascular disease; age less than 20; age more than 50

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Diastolic Blood Pressure. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Heart Rate. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Body Temperature. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Nausea and vomiting. Timepoint: postoperative. Method of measurement: check list.;Shivering. Timepoint: postoperative. Method of measurement: check list.;Systolic blood pressure. Timepoint: before injection,5 minutes after injection, after stability in recovery. Method of measurement: check list.	—

Measure

Time frame

Diastolic Blood Pressure. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Heart Rate. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Body Temperature. Timepoint: before injection, 5 minutes after injection, after stability in recovery. Method of measurement: check list.;Nausea and vomiting. Timepoint: postoperative. Method of measurement: check list.;Shivering. Timepoint: postoperative. Method of measurement: check list.;Systolic blood pressure. Timepoint: before injection,5 minutes after injection, after stability in recovery. Method of measurement: check list.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Nasim Zarrin

Qazvin University of Medical Sciences

zarrinnasim@gmail.com+33 342024

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026