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Efficacy of laser in skin rejuvination

Efficacy and safety of fractional Co2 laser versus fractional Nd:YAG in hand rejuvination

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016032020468N4
Enrollment
36
Registered
2016-03-31
Start date
2016-04-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin rejuvenation. Other specified disorders of skin and subcutaneous tissue

Interventions

Intervention 1: Topical anesthetic gel is applied to both hands and left for 30minutes. The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned to rece
which is focused to a spot size of approximately 5 to 10 micrometer in diameter ,the on time of 0.3 to 20 milliseconds and fluence varies from 10 to 25 J/cm2 .Three treatment sessions with 1 month int
Treatment - Other
Topical anesthetic gel is applied to both hands and left for 30minutes. The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned to receive treatment wi
Topical anesthetic gel is applied to both hands and left for 30minutes. The patient's eyes are covered with a shield during the entire procedure. Patients are randomly assigned to receive treatment w

Sponsors

Shahid Beheshti University of Medical Sciences, Skin Research Center
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: females aged between 45 and 75 years old; patients with mild to moderate hand sun damage. Exclusion criteria: females younger than 45 years old; cosmetic procedures affecting the treatment area (e.g., chemical peeling) within the last 6 months; oral administration of isotretinoin within the last 6 months; history of keloid formation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Skin elasticity. Timepoint: Before treatment, before each session, 3 months after the last session. Method of measurement: Resonance running time, reviscometer.;Rhytides improvement. Timepoint: Before treatment, before each session, 3 months after the last session. Method of measurement: Improvment percentage by comparing digital photoghraphes by dermatologist.;Patient satisfaction. Timepoint: One month after session 1; 1 to three months after session 3. Method of measurement: Patient satisfaction questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElmira Asadi

Skin Research Center

asadielmira8@gmail.com+98 21 2274 1507

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 8, 2026