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Effect of zinc gluconate on acute bronchiolitis

Comparing the effect of Zinc gluconate and placebo in the treatment of tachypnea, dyspnea and fever in children aged 2-23 months with acute bronchiolitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160318027097N12
Enrollment
100
Registered
2018-11-28
Start date
2018-11-22
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute bronchiolitis. Acute bronchiolitis

Interventions

Intervention 1: Intervention group: prescribing syrup Zinc gluconate 1%
produced by Simorgh Darou Attar Company, for 5 days
children younger than 1 year of age will receive 10 mg in two divided doses and those over the age of 1 year will receive 20 mg in two divided doses. Intervention 2: Control group: prescribing Placebo
children younger than 1 year of age will receive 10 mg in two divided doses and those over the age of 1 year will receive 20 mg in two divided doses.

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Months to 23 Months

Inclusion criteria

Inclusion criteria: Aged between 2 to 23 months First episode of wheezing following the viral infection of the upper respiratory tract Presence of clinical manifestations of acute bronchiolitis Absence of consolidation on the chest x-ray

Exclusion criteria

Exclusion criteria: patients with history of more than one episode of wheezing history of asthma and allergy in the patients and their family congenital heart disease malnutrition low birth weight previous antibiotic therapy pneumonia intrauterine growth retardation (IUGR)

Design outcomes

Primary

MeasureTime frame
Tachypnea. Timepoint: Before the intervention; 24 hours, 72 hours and 7 days after the intervention. Method of measurement: Clinical examinations.;Dyspnea. Timepoint: Before the intervention; 24 hours, 72 hours and 7 days after the intervention. Method of measurement: Clinical examinations.;Fever. Timepoint: Before the intervention; 24 hours, 72 hours and 7 days after the intervention. Method of measurement: Clinical examinations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Adel Ahadi

Ardabil University of Medical Sciences

Naghizadeh73@yahoo.com+98 45 3351 2000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026