Primary hypertension. Essential (primary) hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age range between 30-70 years is allowed. According to a specialist doctor's diagnosis, they have primary hypertension and at least one year has passed since their illness Doctors' permission to participate in an exercise program and no need for a specific drug (calcium channel blockers such as verapamil that significantly decrease TXNIP in Langerhans beta cells) (Poudel & Kafle, 2017), at least until Completion of the research period (10 weeks) is required Do not take more than one type of antihypertensive pill daily Their minimum systolic blood pressure was 140 mmHg and diastolic blood pressure was 90 mmHg. They do not have a history of regular exercise in the six months leading up to the time of the study People should not participate in specific weight loss programs Do not have diabetes, fatty liver, Hypothyroidism or hyperthyroidism, anemia (Hb 1.5 mg / dl creatinine) and Do not have a history of Myocardial infarction, heart attack, cardiac arrhythmia Also do not have ischemic heart disease or unstable angina (Farinatti et al., 2016). This informationwill be obtained through the medical records of individuals. They have no history of any heart surgery
Exclusion criteria
Exclusion criteria: Having bone, muscles, and joints problems that prevent exercise. Have a blood pressure higher than 180 mmHg. Take calcium channel blocker drugs such as verapamil, amlodipine, diltiazem. Smoking or addiction to any drug or alcohol (Moraes et al., 2012). Participate in any other exercise program (recreational or professional) while conducting research. Have no interest in participating in a sports activity program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TXNIP Plasma Level. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Enzyme – Linked ImmunoSorbent Assay (ELISA kit for TXNIP).;Plasma insulin levels. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Enzyme – Linked ImmunoSorbent Assay (ELISA kit for insulin).;Fasting glucose. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Enzymatic method of glucose oxidase.;Plasma triglyceride levels. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Spectrophotometry (enzymatic colorimetry) using Pars Test kits.;Plasma total cholesterol levels. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Spectrophotometry (enzymatic colorimetry) using Pars Test kits.;HDL plasma level. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Spectrophotometry (enzymatic colorimetry) using Pars Test kits.;Blood Pressure Number. Timepoint: At the beginning of the study (before the intervention), at the end of the study (after the intervention). Method of measurement: Mercury Pressure Gauge Device. | — |
Countries
Iran (Islamic Republic of)
Contacts
The University of Birjand