The combination of NBUVB, co2 fractional laser treatment of vitiligo

Evaluation of combination treatment by co 2 fractional laser on the margin of lesions and Narrow Band Ultraviolet Band in vitiligo patients referred to Shohada-e- Tajrish and Loghman-e - Hakim hospitals during years 1394- 1396

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016031627072N1

Enrollment

Registered

2016-05-19

Start date

2016-01-28

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

VITILIGO. VITILIGO

Interventions

Intervention 1: Case: The treatment method is, Korean MIXEL, DIOD Laser with 10 to 20 m j energy was used in the 1 cm margin of each lesion in one side. One week after laser, the Patient will exposed

Treatment - Devices

Control: to NBUVB in standard Walkman's cabin with 3 times weekly. Primary energy was 0/1 to 0/2 j/ cm 2, and according to patient's skin tolerance and Treatment response it will be increased to

Case: The treatment method is, Korean MIXEL, DIOD Laser with 10 to 20 m j energy was used in the 1 cm margin of each lesion in one side. One week after laser, the Patient will exposed to NBUVB in sta

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Patients who entered the study were personal satisfaction. 2. under the age of 60 years and more than 18 years. 3 patients (based on the detection dermatologist) with vitiligo . Exclusion criteria: 1. a history of allergy to the sun or UV radiation . 2. person or family history of skin cancer. 3. pregnancy and lactation. 4. ANA test is positive. 5. Fitzpatrick skin type 1. 6. Enable infection or history of skin infection with HSV. 7. Hypertrophic scars or keloids . 8. Heart failure. 9.Patients whit or a history of atypical nevus and melanoma. 10. Patients whit local or systemic treatment during the last three months .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The efficacy of co2 Fractional laser and NBUVB of pigmentation of vitiligo lesions. Timepoint: Monthly until the end of the fourth month and at the end of the sixth month. Method of measurement: Disease severity index based on VASI.	—

Secondary

Measure	Time frame
Side effects. Timepoint: Disease severity index based on VASI. Method of measurement: Ask the patient.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Ghasemloo

Skin Research Center

sara_ghasemloo@yahoo.com+98 21 2274 1507

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026