Blood exchange in COVID-19

Effect of red blood cell exchange on hypoxemia in patients with severe COVID-19

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160316027081N2

Enrollment

Registered

2021-05-13

Start date

2021-04-21

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia due to COVID-19. Pneumonia due to coronavirus disease 2019

Interventions

Intervention 1: Intervention group: after determining the blood group and crossmatch, first a single unit blood sampling equal to 250-300 cc is performed and a unit pack cell is transfused and this pr

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Positive PCR test for COVID-19 Ground glass opacity more than 50% in CT scan RR>30 Severe hypoxemia and O2 sat30, DM, Pulmonary disease, Immune deficiency

Exclusion criteria

Exclusion criteria: Death in 24 hours after admission Transferring to another hospital during treatment Pregnancy

Design outcomes

Primary

Measure	Time frame
Increasing O2 saturation more than 90%. Timepoint: The day 7 and 14. Method of measurement: Pulse oximetry in the room air.	—

Secondary

Measure	Time frame
Mortality rate. Timepoint: The days 7, 14, 28. Method of measurement: Yes/ No.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Aminianfar

Artesh University of Medical Sciences

maminianfar@yahoo.com+98 21 3995 5555

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 12, 2026