Comparing the prophylaxis effects of Metoprolol and Magnesium on prevention of AFatrial fibrillation after CABG ( coronary artery bypass graft)

Comparing the prophylaxis effects of Metoprolol and Magnesium on prevention of atrial fibrillationafter CABG ( coronary artery bypass graft)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016031520258N5

Enrollment

195

Registered

2016-04-17

Start date

2016-04-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation. Other specified complications of cardiac and vascular prosthetic devices, implants and grafts

Interventions

Intervention 1: In the first group inject 5mg Metoprolol. Intervention 2: In second group inject 1.5 grams Magnesium. Intervention 3: Third group inject combination 2.5 mg Metoprolol and 1 grams Ma

Treatment - Drugs

In the first group inject 5mg Metoprolol

In second group inject 1.5 grams Magnesium

Third group inject combination 2.5 mg Metoprolol and 1 grams Magnesium

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients undergoing non-emergency CABG; all patients in ASA class 3 and 4; all patients during surgery is less than 6 hours; all patients without previous history of arrhythmia and atrial fibrillation ; patients without history the anti-arrhythmia Exclusion criteria: All patients during surgery have more than 6 hours; patients undergoing emergency CABG; patients who are undergoing CABG addition valve replacement surgery; patients with a history of previous arrhythmia and AF had before surgery; patients who have a history of taking drugs arrhythmia; patients who have a history of allergy to Magnesium and Metoprolol

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Atrial fibrillation. Timepoint: in operation and after operation until 3 day. Method of measurement: Electrocardiography.;Pulse of heart. Timepoint: in operation and after operation until 3 day. Method of measurement: count.;Respiratory. Timepoint: in operation and after operation until 3 day. Method of measurement: observation.;Temperature. Timepoint: in operation and after operation until 3 day. Method of measurement: Thermometer.;Blood pressure. Timepoint: in operation and after operation until 3 day. Method of measurement: Barometer.	—

Measure

Time frame

Atrial fibrillation. Timepoint: in operation and after operation until 3 day. Method of measurement: Electrocardiography.;Pulse of heart. Timepoint: in operation and after operation until 3 day. Method of measurement: count.;Respiratory. Timepoint: in operation and after operation until 3 day. Method of measurement: observation.;Temperature. Timepoint: in operation and after operation until 3 day. Method of measurement: Thermometer.;Blood pressure. Timepoint: in operation and after operation until 3 day. Method of measurement: Barometer.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzade Hosseini

Arak University of Medical Sciences

alikamaliir@yahoo.com+98 86 3417 3614

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026