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peri-implant crevicular fluid cytokine level using healing abutments

An evaluation to compare peri-implant crevicular fluid cytokine level using intact manufacturer or reused healing abutments: A controlled clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20160315027056N2
Enrollment
50
Registered
2019-08-11
Start date
2019-04-05
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-implant mucositis. Presence of tooth-root and mandibular implants

Interventions

Intervention 1: Intervention group: The group in which reused healing abutment (Dio Pars.Co) is attached to the implant. Intervention 2: Control group: The group in which intact manufacturer healing a

Sponsors

Vice Chancellor for Research and Technology, Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age of the patient should be over 18 Implant treatment should be performed in patients with partial or complete edentulous Bone level implant placement in one stage and obtaining suitable primary stability should be possible. Good patient compliance, reference for follow-up visits and observation of post operation instructions should also be possible.

Exclusion criteria

Exclusion criteria: Patients who have periodontal disease Conditions that affect the immune system such as diabetes and pregnancy The habit of smoking and alcohol or tobacco consumption History of Antibiotics, anti-inflammatory, and immunosuppressive drugs intake three months before the study.

Design outcomes

Primary

MeasureTime frame
Interleukin-1ß cytokine. Timepoint: Two months after the intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) human kits (HANGZHOU EASTBIOPHARM CO.LTD.) for evaluation of interleukin 1ß levels.;Tumor Necrotizing Factor a cytokine. Timepoint: Two months after the intervention. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) human kits (HANGZHOU EASTBIOPHARM CO.LTD.) for evaluation of interleukin 1ß levels.

Secondary

MeasureTime frame
Plaque Index (Ainamo & Bay 1975). Timepoint: 2 months after the intervention. Method of measurement: Observation in such a way that if the plaque is visible on each of the buccal, lingual, mesial or distal surface of healing abutment 0 code and if it is not visible code 1 is assigned.;Bleeding Index (Ainamo & Bay). Timepoint: 2 months after the intervention. Method of measurement: Observation in such a way that if bleeding on probing is visible on each of the buccal, lingual, mesial or distal surface of healing abutment 0 code and if it is not visible code 1 is assigned.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazila Lashkarizadeh

Kerman University of Medical Sciences

nazilalashkarizadeh@yahoo.com+98 34 3211 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026