Prophylactic effects of declonization with chlorhexidine and mupirocin in fever and infection in patients with blood malignancies

Prophylactic effects of global declonization with chlorhexidine and mupirocin on neutropenic fever and infection in patients with acute leukemia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20160310026998N6

Enrollment

Registered

2018-04-13

Start date

2018-02-10

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute leukemia. Neutropenia

Interventions

Intervention 1: Intervention group 1: Patients in first group will use chlorhexidine mouthwash 2 days before till 3 days after chemotherapy (total of 5 days). Intervention 2: Intervention group 2: Sec

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with acute leukemia who receive induction or consolidation regimen as their treatment

Exclusion criteria

Exclusion criteria: Patients who have received antibiotics for treatment goals. patients who have infection or fever. any sensitivity or reverse reaction to mupirocin and chlorhexidine

Design outcomes

Primary

Measure	Time frame
Neutropenic fever. Timepoint: hospitalization duration (days). Method of measurement: oral temperature over 38.3 with Mercuric thermometer.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaba Ghaffary

Tabriz University of Medical Sciences

ghaffarys@tbzmed.ac.ir+98 33266042

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026