weaning of mechanical ventilation.
Conditions
Interventions
Intervention 1: intervention:Budesonide
This group received inhaler Budesonide 1 h before extubation and treatment continued up to 48 h after extubation. Patients underwent the therapy with bude
Treatment - Drugs
intervention:Budesonide
This group received inhaler Budesonide 1 h before extubation and treatment continued up to 48 h after extubation. Patients underwent the therapy with budesonide at a dos
control: Normal Saline
Normal Saline was administered intra venous at a dosage of 0.15 mg/kg, one hour before extubation. After extubation, the administration of normal saline continued at t
Sponsors
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria: intubated patients difficult to wean; duration of ICU stay less than 21 days. The exclusion criteria: patients with bronchiectasis, sepsis or Systemic Inflammatory Response Syndrome, pleural effusion, and Ventilator-Associated Pneumonia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of days of mechanical ventilation. Timepoint: In start of the study and after 5 days. Method of measurement: observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammadreza hashemian
Masih Daneshvari Hospital
Outcome results
None listed