Poly cystic ovary syndrome. Sclerocystic ovarian syndrome
Conditions
Interventions
Intervention 1: Administration of N-acetylcysteine dose of 1.2 grams in day of the third day of menstruation along with clomiphene citrate 100 mg for 5 days of with 5 mg letrozole for 5 days. Interv
Treatment - Drugs
Administration of N-acetylcysteine dose of 1.2 grams in day of the third day of menstruation along with clomiphene citrate 100 mg for 5 days of with 5 mg letrozole for 5 days
Prescription Clomiphene citrate 100 mg for 5 days of treatment with 5 mg letrozole for 5 days
Sponsors
Vice Chancellor for Research Urmia University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: clinical or laboratory signs of hyperandrogenism - Polycystic ovary syndrome sonographic findings (based on the Rotterdam criteria- normal laboratory tests of thyroid- prolactin- normal hysterosalpingography - having infertility due to factors other than male infertility Exclusion criteria: The presence of ovarian cyst- Follicle-stimulating hormone > 10 -patients with ovarian hyper stimulation syndrome (OHSS)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mature follicle. Timepoint: 3 and 11 Days of Menstrual cycle. Method of measurement: The number of Mature follicle.;Endometrial Thickness. Timepoint: Day 11 of Menstrual Cycle. Method of measurement: Endometrial Thickness Measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Abortion rate. Timepoint: 15 days after Intra Uterine Insemination. Method of measurement: clinical examination and ultrasound.;Pregnancy Event. Timepoint: 15 days after Intra Uterine Insemination. Method of measurement: serum ß- HCG measuring. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTahereh Behroozi Lak
Urmia University of Medical Sciences
Outcome results
None listed