epilepsy.
Conditions
Interventions
Intervention 1: L-arginine 2 size of daily need every day for three months. Intervention 2: placebo(starch) 3-6 tablets every day for three months.
Treatment - Drugs
L-arginine 2 size of daily need every day for three months
placebo(starch) 3-6 tablets every day for three months
Sponsors
Neurology Research Center Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: inclusion : patients with epilepsy who have not responses to combination therapy(at least 2 attack per month) by antiepileptic drugs (at least 2 drugs); Exclusion: any disorders except epilepsy; Neurologic disorder except epilepsy; Pregnancy; hypersensitivity or adverse events to L-rrginine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of epileptic attacks. Timepoint: Duration of every attack in one month. Method of measurement: number.;Severity of attacks. Timepoint: duration every attack. Method of measurement: number. | — |
Secondary
| Measure | Time frame |
|---|---|
| Non-tolerance. Timepoint: 3 months. Method of measurement: report. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Ansari
Research manager of Kerman university of medical sciences
Outcome results
None listed